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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ERO1L
All Species:
41.52
Human Site:
S353
Identified Species:
57.08
UniProt:
Q96HE7
Number Species:
16
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96HE7
NP_055399.1
468
54393
S353
E
I
L
H
E
I
K
S
F
P
L
H
F
D
E
Chimpanzee
Pan troglodytes
XP_509950
468
54427
S353
E
I
L
H
E
I
K
S
F
P
L
H
F
D
E
Rhesus Macaque
Macaca mulatta
XP_001103965
468
54383
S353
E
I
L
H
E
I
K
S
F
P
L
H
F
D
E
Dog
Lupus familis
XP_547813
468
54343
S353
E
I
L
H
E
I
K
S
F
P
L
H
F
D
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8R180
464
54066
S349
E
I
L
H
E
I
K
S
F
P
L
H
F
D
E
Rat
Rattus norvegicus
Q8R4A1
464
54000
S349
E
I
L
H
E
V
K
S
F
P
L
H
F
D
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515503
465
53870
S350
K
I
L
Q
E
A
K
S
F
P
L
H
F
D
E
Chicken
Gallus gallus
XP_421473
463
52908
S348
E
V
L
H
L
A
K
S
F
P
L
H
F
D
E
Frog
Xenopus laevis
Q6DD71
465
53720
D351
D
V
L
Q
D
A
R
D
F
P
L
H
F
D
E
Zebra Danio
Brachydanio rerio
Q7T3D1
489
56571
S344
E
L
L
H
V
A
K
S
F
P
L
H
F
D
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3A6
483
55641
N365
D
M
L
S
V
I
E
N
F
Q
S
H
F
D
E
Honey Bee
Apis mellifera
XP_623933
471
55049
S358
D
I
L
N
I
I
K
S
F
P
D
H
F
N
E
Nematode Worm
Caenorhab. elegans
Q7YTU4
478
55136
A346
D
L
L
E
E
I
R
A
Y
P
N
H
F
D
E
Sea Urchin
Strong. purpuratus
XP_796844
897
101920
S777
E
I
L
K
I
A
N
S
F
P
E
H
F
D
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9C7S7
469
53812
L369
Q
F
R
N
I
S
A
L
M
D
C
V
G
C
E
Baker's Yeast
Sacchar. cerevisiae
Q03103
563
65014
N429
K
R
L
N
G
S
E
N
R
L
S
S
F
F
Q
Red Bread Mold
Neurospora crassa
Q7SEY9
668
75589
E348
P
Y
L
S
S
H
E
E
Y
T
F
C
T
G
D
Conservation
Percent
Protein Identity:
100
99.5
98.7
96.3
N.A.
91.8
91.4
N.A.
84.6
77.7
70.9
62.1
N.A.
46.1
48.4
41.4
29.3
Protein Similarity:
100
99.5
99.3
97.8
N.A.
95.9
95.7
N.A.
90.1
85.4
83.9
75.4
N.A.
64.1
65.6
60.8
37.6
P-Site Identity:
100
100
100
100
N.A.
100
93.3
N.A.
80
80
53.3
80
N.A.
46.6
66.6
53.3
66.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
86.6
86.6
80
86.6
N.A.
73.3
86.6
86.6
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
37.9
22.5
22.1
Protein Similarity:
N.A.
N.A.
N.A.
55.6
41.2
38
P-Site Identity:
N.A.
N.A.
N.A.
6.6
13.3
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
20
46.6
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
30
6
6
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
6
6
0
6
0
% C
% Asp:
24
0
0
0
6
0
0
6
0
6
6
0
0
77
6
% D
% Glu:
53
0
0
6
48
0
18
6
0
0
6
0
0
0
89
% E
% Phe:
0
6
0
0
0
0
0
0
77
0
6
0
89
6
0
% F
% Gly:
0
0
0
0
6
0
0
0
0
0
0
0
6
6
0
% G
% His:
0
0
0
48
0
6
0
0
0
0
0
83
0
0
0
% H
% Ile:
0
53
0
0
18
48
0
0
0
0
0
0
0
0
0
% I
% Lys:
12
0
0
6
0
0
59
0
0
0
0
0
0
0
0
% K
% Leu:
0
12
95
0
6
0
0
6
0
6
59
0
0
0
0
% L
% Met:
0
6
0
0
0
0
0
0
6
0
0
0
0
0
0
% M
% Asn:
0
0
0
18
0
0
6
12
0
0
6
0
0
6
0
% N
% Pro:
6
0
0
0
0
0
0
0
0
77
0
0
0
0
0
% P
% Gln:
6
0
0
12
0
0
0
0
0
6
0
0
0
0
6
% Q
% Arg:
0
6
6
0
0
0
12
0
6
0
0
0
0
0
0
% R
% Ser:
0
0
0
12
6
12
0
65
0
0
12
6
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
6
0
0
6
0
0
% T
% Val:
0
12
0
0
12
6
0
0
0
0
0
6
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
6
0
0
0
0
0
0
12
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _